Tennessee’s law bans puberty blockers and hormone treatments for transgender minors, but not “across the board,” lawyers for the families wrote in their Supreme Court brief. The lead lawyer, Chase Strangio of the American Civil Liberties Union, is the first openly transgender person to argue in front of the justices.

The ruling could set a precedent for several challenges to state laws regarding sports participation, bathroom use and health care for adults.

The Supreme Court will hear oral arguments Wednesday over Tennessee’s ban on gender-affirming care for minors, a landmark case that will have implications nationwide as Republicans have increasingly targeted transgender rights and enacted bans on healthcare for minors across the country.