San Francisco 49ers linebacker Fred Warner says he has been playing through a fractured bone in his ankle since Week 4.

We thought San Francisco was poised for a massive second-half run after the Week 9 bye with Christian McCaffrey back, but the ...

The San Francisco 49ers are 5-6 entering their matchup with the Buffalo Bills on Sunday, and an NFL executive called out ...

ATS on my picks in Week 12. However, the good news is that I went 3-2 ATS on my locks of the week, which claws us back over ...

Not interested in this game? Check out expert picks and best bets for every NFL game this week. Buffalo had its bye and the ...

The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in ...

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night.

Deebo Samuel probably is the most disappointing player on the most disappointing team in the NFL through 12 weeks. Despite ...

After routing the undermanned San Francisco 49ers on Thursday, the Green Bay Packers moved up to seventh in the Packers On SI ...

Following their bye week, the Bills (9-2) will take on the San Francisco 49ers (5-6) at Highmark Stadium in Week 13. But ...

San Francisco 49ers quarterback Brock Purdy was limited with the right shoulder injury that sidelined him last week and there ...

Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an ...