One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

The Buffalo Bills have the chance to make team history on "Sunday Night Football" against the San Francisco 49ers.

The Bills are seemingly getting healthy heading into the matchup, as linebacker Matt Milano and receiver Keon Coleman both ...

The snow may taper off by kickoff, but conditions ahead of the Bills game Sunday night could still make travel difficult.

By kickoff, there could be feet of snow on the ground south of Buffalo and nearly two feet in Orchard Park. A lake effect ...

Drones will take the air at Highmark Stadium during the Buffalo Bills game on Sunday night against the San Francisco 49ers.

Buffalo Bills quarterback Josh Allen announced his engagement to actress Hailee Steinfeld on Friday. Allen made the ...

But even when most or all of those Niners took the field this year, closing out games has been a glaring weakness for a team expected to compete for the NFC. A loss to Seattle in Week 11 marked the ...

In this episode of Nine & Dime, Los Angeles Rams quarterback Matthew Stafford and wide receiver Cooper Kupp take a trip down ...

The first big snow of the season has the potential to bury towns in New York along lakes Erie and Ontario during a hectic ...

A look at Friday's Injury Report leading into Sunday's Week 13 regular season game between the Rams and the Saints at Caesars ...

Running back Christian McCaffrey says the San Francisco 49ers are "hungry" to make a playoff push even with the defending NFC ...